Jinesh (AWS) has a great white paper about cloud computing out. The white paper is broken into two main sections:
Building GrepTheWeb in the Cloud, Part 1: Cloud Architectures
Building GrepTheWeb in the Cloud, Part 2: Best Practices and Lessons Learned
The first section of the paper will help you understand the benefits of building applications in-the-cloud; but if you are already a cloud user, the second section will help you more effectively utilize some of the best practices.
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